I had come across an issue where you installed System Center Service Manager, configured the basic settings, then comes the Connectors configuration and you can’t connect your Exchange connector to the Exchange or inbox you want to monitor and process emails into Work Items. I’ve smashed my head a lot against the wall trying to fix this, and surely lots of coffee drinking too.

I even reached Microsoft Support and for days their support team and engineers from  India dug into this (so they said) but could not figure it. That was then when I decided to play with Registry keys. The error is as show below and you might face the same on Windows Server 2016 and 2019.